The data in the attached article identifies supported software options by operating system for the Application Client for WebSphere Application Server V8.0.
This document describes the minimum product levels that need to be installed before opening a problem report with the WebSphere Application Server Support team. Because other products frequently ship fixes, updates, and new releases, testing every configuration is not possible. In general, you can install and run with updates to supported products if those updates are forward compatible.
Read all the information here in an article from IBM.